Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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The Jod-Basedow effect also Jod-Basedow syndrome and Jod-Basedow phenomenon is hyperthyroidism following administration of iodine or iodide, [1] either as a dietary supplement or as contrast medium. In Preedy, Victor R. On the other hand, in a hypothyroid state, thyroid hormone deficiency results in lower heart rate and weakening of myocardial contraction and relaxation, with prolonged systolic and rfecto diastolic times.

In both instances, the underlying cause is the high efecyo of iodine in this medication. Clinical features and treatment outcomes. By using this site, you agree to the Terms of Use and Privacy Policy.

Wolff–Chaikoff effect

Prevalence of thyroid dysfunction and effect of contrast medium on thyroid metabolism in cardiac patients undergoing coronary angiography. La exposici a cantidades excesivas de yodo bloquea la actividad de la enzima peroxidasa tiroidea TPOun feneno conocido como efecto de Wolff-Chaikoff.

Subscriber If you already have your login data, please click here. In general, subclinical hypothyroidism increases the risk of coronary heart disease CHD mortality and CHD events, but not of total mortality. Print Send to a friend Export reference Mendeley Statistics.


To improve our services and products, we use basedos own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. The Jod-Basedow effect is named for the German word for iodine”Jod” all nouns are capitalized in Germanplus the name of Karl Adolph von Basedowa German physician who first described the effect.

Effects of thyroid hormones on the heart | Clínica e Investigación en Arteriosclerosis

CiteScore measures average citations received per document published. Iodine-induced hyper-thyroidism after contrast media.

Views Read Edit View history. Nephrol Dial Transplant ;22 4: Goodman and Gilman’s the pharmacological basis of therapeutics 9th ed. Not to be confused with Basedow’s disease. The Wolff—Chaikoff effect is also part of the mechanism for the use of potassium iodide in nuclear emergencies. Iodine and thyroid disease. Overall, hyperthyroidism is characterized by an increase in resting heart rate, blood volume, stroke volume, myocardial contractility, and ejection fraction.

Por el contrario, cuando un tirocito contiene valores bajos de yodo y es expuesto a elevadas concentraciones del mismo, aumenta de forma significativa la producci de hormona tiroidea, llevando frecuentemente a hipertiroidismo clico y bioquico, feneno conocido como efecto de Jod-Basedow. The Jod-Basedow effect typically occurs with comparatively small increases in iodine intake, in people who have thyroid abnormalities that cause the gland to function without the control of the pituitary i.

Subclinical thyroid dysfunction and mortality: Abstract Exposure to excessive amounts of iodine blocks the activity of the enzyme thyroid peroxidase TPOa phenomenon known as Wolf-Chaikoff effect.

Are you a health professional able to prescribe or dispense drugs? In individuals with a normal thyroid, the gland eventually escapes from this inhibitory effect and iodide organification resumes; however, in patients with underlying autoimmune thyroid disease, the suppressive action of high iodide may persist.


Jod Basedow

Subscribe to our Newsletter. Continuing navigation will be considered as acceptance of this use. Finally, medications such as amiodarone may induce hypothyroidism mediated by the Feectoas well as hyperthyroidism mediated by the Jod—Basedow effect. Cardiac and hemodynamic consequences of hyperthyroidism. Clinically, this effect can lead to hypothyroidism.

The Jod-Basedow phenomenon is differentiated from Basedow’s diseasewhich is occasionally used as a synonym for Graves nasedow. Effect of iodinated contrast media on thyroid function in adults. Animal experimental and clinical studies. Cardiac afterload is increased, and chronotropic and inotropic functions are reduced.

From Monday to Friday from 9 a. Thyroid function after hysterosalpingography using an oil-soluble iodinated contrast medium.

In larger amounts [potassium iodide] acts immediately to block further uptake of iodide by several means, particularly by saturating the iodide transport mechanisms of the thyroid, by inhibiting the intrathyroidal organification of iodide, and by simple dilution.

Med J Aust efevto 4: The Wolff—Chaikoff effect[1] discovered by Drs. Pharmacology for Women’s Health. The Japanese-Brazilian thyroid study.

Universidad Tecnolica de Pereira, Risaralda. Harrison’s Principles of Internal Medicine. Neuroendocrinology Pediatric endocrinology Psychoneuroendocrinology Reproductive endocrinology and infertility. Fortschr Geb Rontgenstrahlen Nuklearmed Ergan- zugsbd ; Si continua navegando, consideramos que acepta su uso. Eur Radiol ;14 5: Eur J Endocrinol ; 3: Med Clin North Am ;96 2: