Gmelina arborea is an important medicinal plant indicated in the traditional Indian medicine. phytochemical constituents of Gmelina arborea leaves using standard methods. The phytochemical analysis revealed the concentrations (mg/g). Gmelina arborea an important medicinal plant is one of the most widely cultivated species of the family Verbenaceae. It is highly valued from time imm.

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After complete extraction, the ME was filtered and concentrated under reduced pressure by using rotary vacuum evaporator. Hosny M, Rosazza PN. An In-vivo study on analgesic and antipyretic activity of bark extracts of gmelina arborea. Preparation of aqueous extract Cold maceration technique was used to prepare AE of bark of G. Pathway to carrageenan-induced inflammation in the hind limb of the rat. The literature suggests use of the plant in treatment of scorpion sting, snake-bites,[ 1 ] and diabetes.

Effect of Gmelina arborea Roxb in experimentally induced inflammation and nociception

The acetic acid induced abdominal constrictions are associated with sensitization of nociceptive receptors to prostaglandins. Anti-inflammatory and analgesic activities from roots of Angelica pubescens. The journal have high circulation and visibility online, thus offer excellent media for promotion of your products, gmelinw or conferences through All experimental hmelina were performed according to the National Institutes of Health NIH guide for the care and use of laboratory animals.


The possible mechanism may also be linked to the inhibition of the production or action of prostaglandins. Powdered bark g was macerated with 1 L of distilled water for 7 days, with occasional shaking.

The present review provides all the references and beneficial directions to explore further application of G.

All the experimental protocols were approved by the Institutional Animal Ethics Committee IAEC constituted as per phytohcemistry norms of committee for the purpose of control and supervision of experiments on animals, India.

Chellappan DR, Pemiah B. Journal of Natural Remedies. Pandey AM, Kulkarni Y. The ability of the extracts to prolong the reaction latency suggests that the extracts have a central analgesic activity. Gmelina arboreais the most widely cultivated species of the family Verbenaceae having potential medicinal values. This article has been cited by other articles in PMC.

Few coumarin glycosides[ 10 ] and iridoid glycosides[ 11 ] have been reported in roots and leaves, respectively. The bark of the G.

An overview on Phytochemistry and Pharmacological properties of Gmelina arborea. Plantation forestry in the tropics Clarendon press, Oxford, UK. J Med Plants Res.


There was significant increase in pain threshold in mice towards the thermal stimuli by hot plate, after treatment with the two extracts [ Table 3 ]. Two new keto-lignans from Gmelina arborea. The second phase of edema is due to the release of prostaglandins, protease and lysosome.

Preliminary phytochemical screening Preliminary phytochemical screening of the aqueous and ME was done phytoche,istry identify presence of diverse phytoconstituents by standard methods. Table 1 Preliminary phytochemical screening of Gmelina arborea extracts. Phytochdmistry discovery and evaluation: J Pharmacol Exp Ther.

Open in a separate window. Chemical constituents from Gmelina arborea bark and their antioxidant activity.

Journal of Pharmacognosy and Phytochemistry

Antioxidant activity of Gmelina arborea Roxb. Toxicity study and analgesic activity of Gmelina arborea extract and its fractions, J Nat Pharm. Occurrence of luteolin in the leaves of Gmelina arborea, Linn.

Antimicrobial screening of selected medicinal plants from India. Any plant which is used medicinally requires detailed study prior g,elina its use for the purpose of identification of the plant, to avoid adulteration with other drugs and also for its therapeutic efficacy.